| Saint Mary's Stadium | — | 5,500 seats | September 22, 1973 |
| Salt Palace | Salt Lake City | — | July 11, 1969 |
| Salt River Fields at Talking Stick | Scottsdale | 11,000 seats | February 11, 2011 |
| San Diego Stadium | San Diego | 70,561 seats | August 20, 1967 |
| SAP Center | San Jose | 19,190 seats | September 7, 1993 |
| Sartain Hall | Alabama | 4,000 seats | 1962 |
| Schoenecker Arena | — | 1,800 seats | 2010 |
| Scotiabank Arena | Old Toronto | 19,800 seats | February 19, 1999 |
| Scotiabank Saddledome | Calgary | 16,605 seats | 1983 |
| Scott Stadium | Albemarle County | 61,500 seats | October 15, 1931 |
| Scottsdale Stadium | Scottsdale | 12,000 seats | March 12, 1992 |
| ScottsMiracle-Gro Field | Columbus | 20,139 seats | July 3, 2021 |
| SeatGeek Stadium | Bridgeview | 20,000 seats | June 11, 2006 |
| Serraglio alla Maddalena | Naples | — | 1742 |
| Sharks Ice San Jose | — | — | 1994 |
| Sheboygan Municipal Auditorium and Armory | Wisconsin | — | May 22, 1942 |
| Shell Energy Stadium | Houston | 22,039 seats | May 12, 2012 |
| Simmons Bank Liberty Stadium | Memphis | 50,160 seats | September 16, 1965 |
| Sloan Park | Mesa | 15,000 seats | February 12, 2014 |
| Smisor Stadium | Kansas | 3,000 seats | — |
| Smith Spectrum | — | 10,270 seats | December 1, 1970 |
| Snapdragon Stadium | San Diego | — | August 19, 2022 |
| SNHU Arena | Manchester | 9,852 seats | November 15, 2001 |
| SoFi Stadium | Inglewood | 70,240 seats | — |
| Soldier Field | Chicago | 63,500 seats | October 9, 1924 |
| South End Grounds I | Massachusetts | 3,000 seats | May 16, 1871 |
| South End Grounds II | Massachusetts | 6,800 seats | May 25, 1888 |
| South End Grounds III | Massachusetts | 5,000 seats | July 20, 1894 |
| South Side Park | Chicago | 15,000 seats | 1890 |
| Sovereign Center | Reading | 9,000 seats | September 6, 2001 |
| Spokane Coliseum | Spokane | 5,400 seats | December 3, 1954 |
| Sporting Park | Kansas City | 25,000 seats | June 9, 2011 |
| Sports Illustrated Stadium | Harrison | 25,189 seats | March 20, 2010 |
| St. Louis Arena | St. Louis | 14,200 seats | September 23, 1929 |
| Stadio del Ghiaccio Gianmario Scola | Canazei | 3,500 seats | 1987 |
| Stadio Olimpico del Ghiaccio | Cortina d'Ampezzo | 12,000 seats | October 26, 1955 |
| Staley Field | Illinois | — | — |
| Stanford Stadium | Stanford | 50,424 seats | September 16, 2006 |
| State Farm Stadium | Glendale | 63,400 seats | August 1, 2006 |
| Stevens Stadium | California | 11,500 seats | September 22, 1962 |
| Stevenson Field | Rhode Island | 3,500 seats | 1979 |
| Stillman Stadium | Alabama | 9,000 seats | 1999 |
| Student Activity Complex | Texas | 8,500 seats | 2004 |
| Subaru Park | Chester | 18,500 seats | June 27, 2010 |
| Surprise Stadium | Surprise | 10,714 seats | December 2002 |
| Sutter Health Park | West Sacramento | 11,093 seats | May 15, 2000 |